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Sandostatin LAR





Sandostatin® is a synthetic somatostatin that acts to regulate growth hormone and growth factors in your body. Sandostatin LAR® Depot is a long-acting form of Sandostatin® manufactured by Novartis Pharmaceuticals Corp.
Sandostatin® is currently FDA-approved for treatment of acromegaly in patients who have had an inadequate response to surgery and/or radiotherapy. It is also approved to treat severe diarrhea from metastatic carcinoid tumors and vasoactive intestinal peptide tumors.
Sandostatin LAR® Depot is given as an intramuscular injection. This medication requires a valid prescription from your prescriber. Ocean Breeze Healthcare can provide Sandostatin LAR® Depot as well as most of the supplies you would need to administer Sandostatin LAR® Depot.

What form is Sandostatin LAR® Depot currently available?

Sandostatin LAR® Depot is available as a single-use vial in 10 mg, 20 mg, and 30 mg strengths.

What are some potential side effects(s) of Sandostatin LAR® Depot?

Sandostatin LAR® Depot is generally well tolerated. While unlikely, possible side effects include, but are not limited to, rash, redness or bruising at the injection site, diarrhea, and abdominal pain. In rare cases, gallbladder abnormalities may occur with use of Sandostatin®.

In rare but serious cases, gallstones may develop while taking Sandostatin®. Tell your doctor immediately if you develop sudden pain in your abdomen or around your shoulder or yellowing of skin or eyes. Sandostatin® can also affect your blood sugar, increase blood pressure and slows heart rate. Monitor symptoms closely if you are on any medication related to the above conditions.

If you are experiencing any unwanted side effect(s) or have any specific questions or concerns regarding a side effect, contact your doctor or pharmacist. You may also report the side effect(s) to the FDA at, or call 1-800-FDA-1088.

How do you administer Sandostatin LAR® Depot?

Sandostatin LAR® Depot should be prepared and administered by a trained health care provider. The drug needs to be injected intramuscularly in the buttocks in order for the medication to work.
Drug must be mixed with the syringe containing diluent to form a suspension before injection. Administer the full content of the drug intramuscularly to the buttock. Alternate the injection site every 4 weeks.

How do you store Sandostatin LAR® Depot?

Sandostatin LAR® Depot must be stored in the refrigerator (36 – 46° Fahrenheit) at all times. Keep the drug protected from the light until ready for use. Sandostatin LAR® Depot should be in room temperature for 30 – 60 minutes prior to preparation of the drug suspension.

How long does Sandostatin LAR® Depot last?

Before opening, the Sandostatin LAR® Depot is stable until the indicated expiration date listed on the packaging, while stored in the refrigerator. Once the drug suspension is prepared, the drug must be used immediately. The vial is for a single use and should be discarded after injection.

Commonly Asked Questions

Q:How do you mix Sandostatin LAR® Depot?
A:Sandostatin LAR® Depot is mixed with diluents solution that comes with the medication to form a suspension.      This should be done by a trained healthcare professional. For details on drug mixing preparation, see          preparation and administration handout.
Q:Are there any preservatives in Sandostatin® Depot?
A:No, Sandostatin LAR® Depot is preservative-free.
Q:How often do I take Sandostatin LAR® Depot?
A:You should take Sandostatin LAR® Depot exactly as prescribed by your doctor. In general, Sandostatin LAR®          Depot is given as a once-a-month injection.

Manufacturer Website

Information on this site is provided for informational purposes and is not meant to substitute for the advice provided by your own physician or other medical professional. You should not use the information contained herein for diagnosing or treating a health problem or disease, or prescribing any medication. You should read carefully all product packaging. If you have or suspect that you have a medical problem, promptly contact your health care provider. Pursuant to 21 U.S.C. § 333 (e) (1), which limits usage only to the treatment of disease or other recognized medical conditions authorized by the Secretary of Health and Human Services, Ocean Breeze Healthcare does not dispense human growth hormone for anti-aging, cosmetic or performance enhancement purposes.


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