Cetrotide® (cetrorelix acetate for injection) is a gonadotropin-releasing hormone (GnRH) blocker used to control hormone responses during ovulation induction. Cetrotide® is a prescription medication manufactured by EMD Serono.
Cetrotide® is currently FDA-approved for use in women for infertility treatment. Cetrotide® is shown to prevent premature ovulation, allowing eggs to fully mature for fertilization.
Cetrotide® requires a valid prescription from your prescriber. Ocean Breeze Healthcare can provide Cetrotide® as well as all the supplies needed to administer Cetrotide®.

What form is Cetrotide® currently available?

Bravelle® is available in a single-dose injection vial.

The Cetrotide® vial is available in 2 strengths: 0.25 mg and 3 mg of active drug. The vial needs to be reconstituted, or mixed, with its diluent (the clear liquid inside the syringe) provided in the same box as the drug vial.

What are some potential side effects of Cetrotide®?

The most common side effects include, but are not limited to, headache, nausea, and injection related reaction such as bruising, redness or itching at the area of injection.

Cetrotide® can cause ovarian hyperstimulation syndrome (OHSS) in women. Common symptoms of OHSS include severe pelvic pain, shortness of breath, and weight gain.

These are not all the possible side effects of Cetrotide®. If you are experiencing any unwanted side effect(s) or have any specific questions regarding a side effect, contact your doctor or pharmacist. You may also report the side effect(s) to the FDA at www.fda.gov/medwatch, or call 1-800-FDA-1088.

Who should NOT use Cetrotide®?

Do not take Cetrotide® if you are already pregnant. Women with kidney disease, or hypersensitivity to cetrorelix acetate, mannitol or to other peptide hormones should not use Cetrotide®.

Talk to your doctor if you are nursing to discuss the benefit versus risk of using Cetrotide®. It is not known if the drug will be passed into mothers' milk.

How do you administer Cetrotide®?

Cetrotide® needs to be injected subcutaneously in order for the medication to work.

The Cetrotide® vial needs to be reconstituted with the diluents before injection. All the syringe and needles required to mix and inject the medication will be supplied together with your medication. For detailed injection instructions Cetrotide®, please read its self-administration guide (PDF: Cetrotide instructions for use).

How do you store Cetrotide®?

Store all Cetrotide® products away from direct light.
Cetrotide® 0.25 mg vial must be stored in refrigerator (34 - 46°F) until expiration date.
Cetrotide® 3 mg vial may be stored in room temperature (59 - 86°F) until expiration date.

How long does Cetrotide® last?

Cetrotide® is valid until expiration date when stored in the appropriate condition. Once the medication is mixed, the preparation must be used immediately.

Commonly Asked Questions

Q:How do you mix Cetrotide® for injection?
A: Cetrotide® vial needs to be mixed with diluent prior to administration. Inject the prefilled syringe of sterile water into the vial. Gently swirl, do not shake. For instructions, please read the injection guide. (PDF: Cetrotide instructions for use)
Q:Are there any preservatives in Cetrotide®?
A: Cetrotide® contains mannitol.
Q:How do I take Cetrotide®?
A:You should inject Cetrotide® under the skin, exactly at the time and dose prescribed by your doctor.

Manufacturer Website


Information on this site is provided for informational purposes and is not meant to substitute for the advice provided by your own physician or other medical professional. You should not use the information contained herein for diagnosing or treating a health problem or disease, or prescribing any medication. You should read carefully all product packaging. If you have or suspect that you have a medical problem, promptly contact your health care provider.


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