Extavia

 

EXTAVIA®

 

[INTERFERON BETA-1b]

 
Extavia® belongs to a class of drugs known as immunomodulators. Extavia® is a synthetic form of human protein called interferon beta, made by Novartis Pharmaceuticals Corp. Interferon is a type of protein that helps to mediate your body’s immune system. Extavia

Extavia® is currently FDA-approved for treating relapsing forms of multiple sclerosis (MS). Clinical studies show that Extavia® reduces the signs and symptoms of MS by decreasing the frequency of flare-ups and slowing progression of MS symptoms.

Extavia® is given as a subcutaneous injection. Extavia® requires a valid prescription from your prescriber. Ocean Breeze Healthcare can provide Extavia® as well as most of the supplies you would need to administer the drug.

What form is Extavia® currently available?

Extavia® is currently available as a single-use vial.

The single-use vial is formulated as dry powder that needs to be mixed with the syringe containing 1.2ml liquid mixing solution (diluent) for subcutaneous injection. Each vial contains 0.3mg/1.0ml dose of interferon beta-1b.

What are some potential side effects of Extavia®?

Common side effects with Extavia® include, but are not limited to, injection site reactions, such as rash, redness or bruising. Other possible side effects are flu-like symptoms, fatigue, headache, lymphopenia, muscle weakness, leucopenia, depression, and liver, blood, or thyroid problems. If you are experiencing any unwanted side effect(s) or have any specific questions or concerns regarding a side effect, contact your doctor or pharmacist. You may also report the side effect(s) to the FDA at www.fda.gov/medwatch, or call 1-800-FDA-1088.

Who should NOT use Extavia®?

Extavia® should be avoided in those with a history of allergy and/or hypersensitivity to interferon beta, human albumin or to any other component of the formulation.

Speak to your doctor or pharmacist if you are pregnant, nursing, or have history of seizures.

How do you administer Extavia®?

Extavia® must be injected under the skin, as a subcutaneous (SQ) injection. Each Extavia® vial is for one-time administration only.

Before Extavia® is ready for subcutaneous injection, the dry powder vial must to be mixed with the sterile diluent syringe to form a solution. Use the vial adapter, provided in the drug package, for reconstitution. Gently swirl the vial to completely dissolve the white cake of Extavia®. DO NOT SHAKE. The reconstituted solution should be clear, colorless and free of particles. Otherwise, contact your doctor or pharmacist.

Once the vial is mixed (reconstituted), pull the plunger back to withdraw the content from the vial, then removed the attached vial adapter and the vial from the syringe before subcutaneous injection. See Extavia Injection Training Guide for details.

Extavia

Novartis Pharmaceuticals also have an injection device, called Extavia Auto-Injector II, as an alternative to regular manual syringe injection. Prime the Extavia Auto-Injector II device for use. Then, insert the reconstituted drug syringe into the syringe housing and attached the injector body. Once ready, press the release button on the Extavia Auto-Injector II to automatically inject the syringe content into the skin. See Extavia Injection Training Guide for details.

How do you store Extavia®?

Extavia® should be stored at room temperature (59° - 86° Fahrenheit) prior to reconstitution. DO NOT FREEZE. Protect from light.

After reconstitution, Extavia® should be used immediately or may be refrigerated for up to 3 hours.

How long does Extavia® last?

Before opening, Extavia® is stable until the indicated expiration date listed on the packaging if all the required storage conditions are met. Once the vial is mixed, it is stable for up to 3 hours under refrigeration. Each vial is intended for one time use only; discard any unused drug after each dose.

Commonly Asked Questions

Q:Does Extavia® cure multiple sclerosis (MS)?
A:No, Extavia® is not a cure for MS. It simply relieves the symptoms associated with MS and may potentially         slow the progression of MS.
 
Q:How do I use Extavia® with the Extavia Auto-Injector II device?
A:First prime the Extavia Auto-Injector II device, then insert the reconstituted Extavia® syringe into the device for         subcutaneous injection. For detailed instructions, please refer to Extavia® Injection Training Guide.
 
Q:Are there any preservatives in Extavia®?
A:No, Extavia® does not contain any preservatives.
 
Q:How often do I take Extavia®?
A:You should inject Extavia® at the exact dose as prescribed by your doctor. In general, Extavia® is given every         other day. Do not take Extavia® two days in a row on consecutive days.

Manufacturer Website

http://www.extavia.com/

Information on this site is provided for informational purposes and is not meant to substitute for the advice provided by your own physician or other medical professional. You should not use the information contained herein for diagnosing or treating a health problem or disease, or prescribing any medication. You should read carefully all product packaging. If you have or suspect that you have a medical problem, promptly contact your health care provider.

 

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